UK-wide trial

Patients from across England and Scotland participated in the trial and were treated in two centres, Royal Brompton Hospital in London and the Western General Hospital in Edinburgh: July 2015

Patients from across England and Scotland participated in the trial and were treated in two centres, Royal Brompton Hospital in London and the Western General Hospital in Edinburgh.

The study was carried out by the UK Cystic Fibrosis Gene Therapy Consortium, a group of scientists and clinical teams from Imperial College London, the Universities of Oxford and Edinburgh, Royal Brompton & Harefield NHS Foundation Trust and NHS Lothian. The findings are published in The Lancet Respiratory Medicine. The trial was funded by the National Institute for Health Research and the Medical Research Council.

"We are naturally encouraged by the outcome of the trial, and are actively investigating how to make non-viral gene therapy for CF more effective by modifying the design of follow-on clinical trials. It is fitting that the Scottish arm of the trial, enrolling patients from NE England and every part of Scotland, took place at the Western General Hospital campus where important early work on CF genetics and gene therapy was pioneered by Professor Julia Dorin and Professor David Porteous."

Dr Christopher Boyd Centre for Genomic and Experimental Medicine, University of Edinburgh