Patrick Hadoke Research Group
Information on the research interests, projects, and members of Patrick Hadoke's Research Group.
Dr Patrick Hadoke
I am interested in mechanisms that regulate arterial function and structure in health and disease, focussing on the role of the endothelium, new blood vessel formation (angiogenesis), and lesion formation (atherosclerosis, neointimal proliferation). Current research projects address: the potential use of cellular therapies to stimulate angiogenesis in ischaemic tissue; the influence of glucocorticoids on angiogenesis; the role of androgens in regulation of atherosclerosis and angiogenesis; and, the influence of the Wilms' Tumour suppressor on new blood vessel formation. My group uses a combination of in vitro, ex vivo and in vivo techniques to address these topics, with a strong focus on the use of novel imaging techniques to improve analysis.