Edinburgh Cancer Research

Latest News

The following news articles were published in 2023.

£4m for Scotland Will Help Find New Cancer Treatments

The development of new cancer treatments in Scotland is to receive major funding of up to £4m providing future hope for people diagnosed with the disease: January 2023

Transcriptomic profiling may identify patients with breast cancer who can safely omit radiation therapy after breast-conserving surgery

Patients with invasive breast cancer that had low scores on an investigational gene molecular signature had similar rates of local recurrence whether or not they received adjuvant radiation therapy after breast-conserving surgery: December 2022

Identification of a signalling axis associated with immune suppression and poor prognosis in pancreatic cancer

Graphical summary of a proposed mechanism through which FAK-IL6 signalling amplifies PD-L2 expression in PDAC
Using animal modelling and human transcriptomic datasets, Edinburgh researchers demonstrated that FAK-IL6 signalling amplifies pathways associated with immune suppression and poor patient prognosis in pancreatic ductal adenocarcinoma.

ecDNA copy number is key to high-level oncogene expression, new research shows

A recent study has demonstrated that, contrary to recent reports, the transcriptional output of oncogenes carried on extrachromosomal DNA in glioblastoma stem cells is driven by the copy number of the ecDNA, rather than their spatial localization into transcriptional hubs: December 2022

Longest follow-up of patients with early breast cancer shows radiotherapy does not improve survival after 30 years

Radiotherapy after breast conserving surgery in conjunction with chemotherapy or tamoxifen to treat early breast cancer reduces the risk of the disease returning in the same breast in the next ten years but makes little difference to that risk thereafter. Nor does it improve overall survival after 30 years.