New zebrafish model sheds light on glioblastoma tumours
Congratulations to the Sieger lab on publishing their study on a new zebrafish microglia-glioblastoma model, which uncovered new findings on the complex interactions between microglia and glioblastoma cells.
Glioblastoma is the most common and most aggressive brain tumour. These tumours are highly infiltrated by microglia which are the resident immune cells of the brain and are meant to protect our brain. However, their response to glioblastomas is detrimental; instead of fighting the tumour microglia actively support tumour growth.
The new zebrafish model will help to understand the mechanisms triggering this behaviour and to identify new drugs that convert microglial activity within the glioblastoma.
This publication has received extensive world media coverage and Cancer Research UK, who fund the Sieger lab, have covered the study in their latest science blog.
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