Professor William G Hill
Telephone: +44 (0) 131 650 5705
Website: No details available
Group members: No details available
|1965||Ph.D., Department of Genetics, University of Edinburgh|
|1979||Fellow of the Royal Society of Edinburgh|
|1985||Fellow of the Royal Society|
|1965-1983||Lecturer, Reader in Genetics, University of Edinburgh|
|1983-2002||Professor of Animal Genetics|
|2003-Present||Emeritus Professor of Animal Genetics|
Population Genetics, Animal Breeding
I undertake theoretical studies on population and quantitative genetics and on their application to animal improvement and to understanding of evolution. I no longer maintain any lab or experiments. Much research is in collaboration with the Roslin Institute, SAC, the animal breeding industry and groups elsewhere, including those of Weir in Seattle and Visscher in Brisbane. I am interested in what maintains variation in complex traits within populations, both the genetic and the environmental components, and in particular the role of mutations. Thus we are developing theory aimed at explaining levels of, for example, heritability, and in considering breeding programmes which influence the homogeneity of livestock products. My other research is primarily on inferences about population structure using marker data, particularly on linked loci, including development of theory and analytical methods.
Hill, W.G., Goddard, M.E. and Visscher, P.M. 2008. Data and theory point to mainly additive genetic variance for complex traits. PLoS Genetics (in press).
Hill, W.G. and Hernandez-Sanchez, J. 2007. Prediction of multi-locus identity-by-descent. Genetics 176: 2307-2315.
Mulder, H.A., Bijma, P. and Hill, W.G. 2007. Prediction of breeding values and selection responses with genetic heterogeneity of environmental variance. Genetics 175: 1895-1910.
Rowe, S.J., White, I.M.S., Avendano, S. and Hill, W.G. 2006. Genetic heterogeneity of residual variance in broiler chickens. Genet. Sel. Evol. 38: 617-635.
Weir, B.S., Cardon, L.R., Anderson, A.D., Nielsen, D.M. and Hill, W.G. 2005. Measures of human population structure show heterogeneity among genomic regions. Genome Res. 15: 1468-1476
Zhang, X.-S. and Hill, W.G. 2005. Evolution of the environmental component of the phenotypic variance: stabilizing selection in changing environments and the cost of homogeneity. Evolution 59: 1237-1244.
Zhang, X.-S., Wang. J. and Hill, W.G. 2004 .Influence of dominance, leptokurtosis and pleiotropy of deleterious mutations on quantitative genetic variation at mutation-selection balance. Genetics 166: 597-610.
Weir, B.S. and Hill, W.G. 2002. Estimating F-statistics. Ann. Rev. Genet. 36:721-750.
Thomas, S.C. and Hill, W.G. 2000. Estimating quantitative genetic parameters using sibships reconstructed from marker data. Genetics 155: 1961-1972.
Hill, W.G. 2000. Maintenance of quantitative genetic variation in animal breeding programmes. Livest. Prod. Sci. 63: 99-109.