Dr Attila Molnar
Location: Rutherford 1.02A
Telephone: 650 5335
Website: No details available
Group members: Yue Fei, PhD student; Muriel Monteiro, PhD student; Aron Ferenczi, PhD student
|2013 - Present||Chancellor's Fellow, University of Edinburgh|
|2007 - 2013||Postdoctoral Research Fellow, Senior Research Associate, University of Cambridge|
|2003 - 2007||Postdoctoral Research Fellow, The Sainsbury Laboratory, John Innes Centre, Norwich|
|2003||Ph.D., Eotvos Lorand University, Budapest, Hungary|
Molecular Plant Sciences
Applied Plant Biology 3 (Course Organiser)
The Microbial World 2
PhD Studentships for 2019
Will be announced later this year.
Small non-coding RNA (sRNAs) molecules are key components in many biological processes, including development, stress-response and disease control against molecular parasites such as viruses and transposons. They mediate post-transcriptional gene silencing that involves mRNA cleavage/destabilization or translational inhibition as well as RNA-dependent DNA methylation and histone modifications that can lead to transcriptional gene silencing. My laboratory studies the synthesis and action of sRNAs with particular emphasis on epigenetic modifications driven by sRNA molecules using a combination of biological systems including plants and viruses and the latest high throughput sequencing technologies.
We aslo develop novel genome editing tools and strategies for functional genomics.
Ferenczi, A., Pyott, D., Xipnitou, A., Molnar, A. (2017). Efficient targeted DNA replacement in Chlamydomonas reinhardtii using single-stranded oligodeoxynucleotides and Cpf1 ribonucleoproteins. PNAS, DOI: 10.1073/pnas.1710597114
Pyott, D.E., Sheehan, E. and Molnar, A. (2016) Engineering of CRISPR/Cas9-mediated potyvirus resistance in transgene-free Arabidopsis plants, Molecular Plant Pathology, 2016 Apr 21, doi: 10.1111/mpp.12417
Publications at Google Scholar