Danny Reinberg, Howard Hughes Medical Institute, New York, USA
17th May 2017 at 12:00pm [Download iCalendar / .ics file]
Epigenetics encompasses changes in gene expression profiles that occur without alterations in the genomic DNA sequence of a cell. This arises from the dynamic processes that structure regions of chromosomal DNA through a range of compaction in eukaryotes. The altered pattern of gene expression is pivotal to cellular differentiation and development and is inherited by daughter cells thereby maintaining the integrity, specifications, and functions for a given cell type. Aberrancies in this epigenetic process give rise to perturbations that are also inherited and disruptive to normal cellular properties.
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