A full range of hepatobiliary, pancreatic, endoscopic, radiological and surgical interventions are available. Management of patients with Hepatobiliary and Pancreatic Malignancy is co-ordinated through the weekly multi-disciplinary meeting. This has regular involvement from the: nine consultant surgeons three oncologists four radiologists one hepatologists two pathologists Royal Infirmary of Edinburgh Clinic A joint surgical/medical/oncology clinic is held at the Royal Infirmary of Edinburgh on a weekly basis on Tuesday afternoons. Approximately 120 liver resections per year are undertaken for primary and secondary tumours of the liver and proximal bile ducts. Major pancreatic resections and pancreatico-duodenectomy (approximately 60 per year) are undertaken for pancreatic cancer and distal cholangiocarcinoma. We also act a tertiary referral centre for the management of bile duct injuries, HPB trauma and patients with severe acute pancreatitis. Procedures A full range of endoscopic and interventional radiological procedures are available for the assessment and treatment of all pancreatico-biliary conditions. These procedures include: endoscopic retrograde cholangiopancreatography (ERCP) percutaneous transhepatic cholangiography (PTC) endoscopic ultrasound (EUS) spyglass chemoembolisation portal vein embolisation Laparoscopy Our advanced laparoscopic procedures include: staging of hepatobiliary and pancreatic malignancy de-roofing of liver cysts pancreatic and hepatic resections minimally invasive pancreatic necrosectomy Laparoscopic cholecystectomy and laparoscopic exploration of the common bile duct are also performed.