Study modes: Full-time, Part-time
Programme website: Clinical Brain Sciences
The Centre for Clinical Brain Sciences (CCBS; Director Professor Siddharthan Chandran) integrates laboratory and clinical research to study the causes, consequences and treatment of major brain disorders.
Anchored in the Edinburgh Bioquarter at the Royal Infirmary of Edinburgh, and with bases at three other Edinburgh hospital sites, the centre subscribes to Edinburgh Medical School’s "One Health" vision: laboratory scientists, clinical academics and informaticians work alongside each other, to encourage the free-flowing exchange of ideas, the efficient use of clinical data, and joint academic/health service delivery.
CCBS is part of Edinburgh Neuroscience, an umbrella organisation that facilitates interaction among researchers, working at all levels of neuroscience from molecules through synapses and networks to cognition and behaviour. In the most recent Research Excellence Framework (2014), Edinburgh was ranked 3rd out of 82 submissions in Neuroscience and the research environment was given the maximum possible score - 100%, world-leading.
CCBS comprises 60 Principal Investigators - including 21 Chairs - of whom 70% are active NHS clinicians. The Centre’s 400+ members conduct research of international recognition and reputation: they attracted c.£40M in grant-funding over the last three years and collaborate widely, leading international clinical trials in stroke (e.g. IST-3) and dementia (e.g. EPAD), while The National CJD Research and Surveillance Unit is a World Health Organization Reference Centre for Human Prion Disease. The research generates significant and measurable impact in terms of patient health and wellbeing, NHS policy and economy, and public awareness.
Major disease-specific research strengths are:
For more information, see our website:
Postgraduate students are mentored and supported by at least two supervisors and receive long-term guidance from their thesis committee.
We offer a transferable skills programme and project-specific courses, including opportunities to become involved in science communication and public engagement.
PhD meetings and an annual CCBS Day provide valuable opportunities for interdisciplinary collaboration.
Direct clinical links, Specialist Centres of Excellence, well characterised patient cohorts, national biobanks and disease registers permit detailed phenotyping for surveillance, clinical epidemiological studies and trials.
Find more information on the research centres:
The Anne Rowling Regenerative Neurology Clinic provides an interface between patients and researchers and space to conduct studies. We also have expertise in meta-analysis & systematic review (e.g. CAMARADES, Cochrane Stroke Group).
CCBS is part of Edinburgh Imaging, which provides state-of the-art imaging for preclinical and clinical studies: 1.5T research MR scanner; 3T MR scanner; PET MRI, PET-CT; 7T animal MR; image analysis suites including fMRI compatible EEG.
We are expert in detailed pathological analysis of post-mortem human brain tissue, and run the Edinburgh Brain and Tissue Banks (part of the MRC UK Brain Banks Network). The Edinburgh Brain Banks include CJD, HIV, stroke, motor neurone disease, dementia and sudden death banks.
Our laboratories are fully equipped for molecular biology, protein biochemistry & cell biology research, including large-scale studies (e.g., molecular analyses of multiprotein complexes at the synapse). CCBS researchers use patient-derived (induced pluripotent) and human embryonic stem cells to model disease processes using confocal microscopy, electrophysiology, FACS and biochemistry.
An emerging area of interest for CCBS, the research aims to inform, enable and accelerate the translation of advances from the laboratory to the operating theatre, with a focus on neuro-oncology.
Find more information on our research methodologies on our website
The minimum entry requirement for our research programmes is an undergraduate degree, with an excellent or very good classification (equivalent to first or upper-second class honours in the UK). For some non-UK applicants the entry requirement is a masters degree. Please check the entry requirements by country.
Check whether your international qualifications meet our general entry requirements:
If English is not your first language, you must have one of the following qualifications as evidence of your spoken and written English:
If you completed a CAE or CPE before January 2015 please contact the Admissions Office for the accepted grades.
Find out more about our language requirements:
For detailed information on fee status, policies and payment see:
You will be responsible for securing funding to cover all your tuition fees, additional fees and living costs for the duration of your studies. For guidelines on living costs see:
See Scholarships and Student Funding Services for other funding opportunities:
Select your programme and preferred start date to begin your application.
We encourage you to apply at least one month prior to entry so that we have enough time to process your application. If you are also applying for funding or will require a visa then we strongly recommend you apply as early as possible. We may consider late applications if we have places available, but you should contact the relevant Admissions Office for advice first.
You must submit two references with your application.
Before making your application, you must make contact with a potential supervisor to discuss your research proposal. Further information on making a research degree application can be found on the College website:
You will be formally interviewed (in person, by video-conferencing or Skype).
Find out more about the general application process for postgraduate programmes: