Professor Andrew McIntosh

Andrew McIntosh is Chair of Biological Psychiatry at the University of Edinburgh and Associate Director of the Scottish Mental Health Research Network.

Andrew McIntosh
  • Professor Andrew M McIntosh
  • Chair of Biological Psychiatry
  • Division of Psychiatry
  • Work: 0131 537 6688
  • Fax: 0131 537 6291

He is an Honorary Consultant Psychiatrist in NHS Lothian.


Professor McIntosh graduated in Medicine from Aberdeen University in 1995 and Psychiatry training within Scotland.

He has held several posts, including that of Wellcome Trust Research Fellow, MRC Research Fellow, Academy of Medical Sciences/Health Foundation Clinician Scientist, Reader and Visiting Associate Professor at Yale Medical School.

Research interests

Professor McIntosh's goal is to identify and use genetic risk factors for psychiatric disorder in order to elucidate their underlying disease mechanisms using measures of brain structure, function and connectivity.

Markers of esteem

Selected publications

Polygenic risk and white matter integrity in individuals at high risk of mood disorder
Biol Psychiatry. 2013;74(4): 280-286
Whalley HC, Sprooten E, Hackett S, Hall L, Blackwood DH, Glahn DC, ...
Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age
Biol Psychiatry. 2013;73(10): 938-943
McIntosh AM, Gow A, Luciano M, Davies G, Liewald DC, Harris SE, Deary IJ
White matter integrity in individuals at high genetic risk of bipolar disorder
Biol Psychiatry. 2011;70(4):350-6
Sprooten E, Sussmann JE, Clugston A, Peel A, McKirdy J, Moorhead TW, Anderson S, Shand AJ, Giles S, Bastin ME, Hall J, Johnstone EC, Lawrie SM, McIntosh AM
The neural basis of familial risk and temperamental variation in individuals at high risk of bipolar disorder
Biol Psychiatry. 2011;70(4):343-9
Whalley HC, Sussmann JE, Chakirova G, Mukerjee P, Peel A, McKirdy J, Hall J, Johnstone EC, Lawrie SM, McIntosh AM
Association of white matter integrity with genetic variation in an exonic DISC1 SNP
Mol Psychiatry. 2011;16(7):688-9
Sprooten E, Sussmann JE, Moorhead TW, Whalley HC, Ffrench-Constant C, Blumberg HP, Bastin ME, Hall J, Lawrie SM, McIntosh AM
Longitudinal volume reductions in people at high genetic risk of schizophrenia as they develop psychosis
Biol Psychiatry. 2011 May 15;69(10):953-8
McIntosh AM, Owens DC, Moorhead WJ, Whalley HC, Stanfield AC, Hall J, Johnstone EC, Lawrie SM

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