Division of Psychiatry Division of Psychiatry
Key researchers

Dr Mandy Johnstone

Mandy Johnstone is a Clinical Lecturer in Psychiatry.

Mandy Johnstone
  • Mandy Johnstone
  • Lecturer
  • Division of Psychiatry
  • Work: 0131 537 6696
Email:

Background

Dr Johnstone completed her PhD in Developmental Neurobiology at King’s College London.

She qualified in Medicine at the University of Glasgow and then went on to train as a psychiatrist at The Institute of Psychiatry/South London and The Maudsley and then in Edinburgh on the South East Scotland Rotation.

Research interests

Dr Johnstone’s research interests are in the clinical and molecular genetics of schizophrenia and affective disorders and currently she is investigating whether copy number variants (CNVs) contribute to susceptibility in families multiply affected with schizophrenia and bipolar affective disorder.

During her psychiatric training, she was struck by the devastating effects that schizophrenia has on those afflicted and their families and would like to gain a greater understanding of the development of the disorder with the principal goal of improving treatment and patient care.

Her research is funded by grants from The Academy of Medical Sciences and The Wellcome Trust and from The RS MacDonald Charitable Trust.

Selected publications

MAQ screening the ABCA13 gene for copy number variation in schizophrenia and bipolar disorder
Psychiatric Genetics (in press)
Pickard BS, Van Den Bossche MJA, Malloy MP, Johnstone M, Lenaerts AS, Nordin A, Goossens D, St Clair D, Muir WJ, Nilsson L-G, Bernard S, Adolfsson R, Blackwood DHR, and Del-Favero J (2011)
DISC1 in schizophrenia: Genetic mouse models and human genomic imaging
Schizophrenia Bulletin, 37: 14-20
Johnstone M, Thomson PA, Hall J, McIntosh A, Lawrie SM & Porteous DJ (2011)
A central role for astrocytes in the inflammatory response to -amyloid: chemokines, cytokines and reactive oxygen species are produced
Journal of Neuroimmunology, 93:182-193
Johnstone M, Gearing AJH & Miller KM (1999)
Localisation of microtubule-associated protein 1B phosphorylation sites recognised by monoclonal antibody SMI-31
Journal of Neurochemistry, 69:1417-1424
Johnstone, M, Goold RG, Bei D, Fischer I & Gordon-Weeks PR (1997)
The neurofilament antibody RT97 recognises a developmentally regulated phosphorylation epitope on microtubule-associated protein (MAP) 1B
Journal of Anatomy, 191:229-244
Johnstone M, Goold RG, Fischer I & Gordon-Weeks PR (1997)
A phosphorylation epitope on MAP1B that is transiently expressed in growing axons in the developing rat nervous system
European Journal of Neuroscience, 5:1302-1311
Gordon-Weeks PR, Mansfield SG, Alberto C, Johnstone M & Moya F (1992)

This article was published on Oct 5, 2011


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