Division of Psychiatry Division of Psychiatry
Key researchers

Dr Bill Moorhead

Bill Moorhead is a Post Doctoral Scientist in the Division of Psychiatry.

Bill Moorhead
  • Dr Bill Moorhead
  • Post Doctoral Scientist
Email:

In his post, Dr Moorhead is working on the development of MRI analysis methods for longitudinal studies of psychosis.

Background

After completing his HND in 1977, Dr Moorhead worked on avionics systems at Ferranti Defence Systems in Edinburgh. In this he advanced to become a Senior Instrumentation Engineer in the Electro Optics Research Laboratory.

After completing his MSc in 1995, he took up a post lecturing on Artificial Intelligence and instrumentation at Napier University.

In 2001 he completed his PhD research into low level vision processing employing novel sub-threshold complementary metal oxide silicon devices, and took up a Research Fellow post at Napier and worked on modelling novel amorphous silicon devices.

He took up his current post with the Division of Psychiatry in 2003.

Research interests

Dr Moorhead is involved in the development 3-dimensional machine tracing techniques designed to extract of information from MRI scans with a specific focus on the subtle variations brain morphology that can point to an increased vulnerability to the development of illness.

He has also been working on the implementation multi-spectral scanning. The current focus of this work has been on obtaining high-quality co-registration of structural, functional, perfusion and diffusion imaging. The multi-spectral work also includes MRI spectroscopy assays of brain metabolites.

Selected publications

Longitudinal volume reductions in people at high genetic risk of schizophrenia as they develop psychosis
Biol Psychiatry. 2011 May 15;69(10):953-8.
McIntosh AM, Owens DC, Moorhead TWJ, Whalley HC, Stanfield AC, Hall J, Johnstone EC, Lawrie SM
Reduced prefrontal gyrification in obsessive-compulsive disorder
Eur Arch Psychiatry Clin Neurosci. 2010 Sep;260(6):455-64
Wobrock T, Gruber O, McIntosh AM, Kraft S, Klinghardt A, Scherk H, Reith W, Schneider-Axmann T, Lawrie SM, Falkai P, Moorhead TWJ
Progressive temporal lobe grey matter loss in adolescents with schizotypal traits and mild intellectual impairment
Psychiatry Research: Neuroimaging 2009 Nov 30;174(2):105-9
Moorhead TWJ, Stanfield A, Spencer M, Hall J, McIntosh A, Owens DC, Lawrie S, Johnstone E
Prospective multi-centre Voxel Based Morphometry study employing scanner specific segmentations: procedure development using CaliBrain structural MRI data
BMC Med Imaging. 2009 May 15;9:8.
Moorhead TWJ, Gountouna VE, Job DE, McIntosh AM, Romaniuk L, Lymer GK, Whalley HC, Waiter GD, Brennan D, Ahearn TS, Cavanagh J, Condon B, Steele JD, Wardlaw JM, Lawrie SM
Structural abnormalities of ventrolateral and orbitofrontal cortex in patients with familial bipolar disorder
Bipolar Disord. 2009 Mar;11(2):135-44
Stanfield AC, Moorhead TWJ, Job DE, McKirdy J, Sussmann JE, Hall J, Giles S, Johnstone EC, Lawrie SM, McIntosh AM
Changes in gyrification over 4 years in bipolar disorder and their association with the brain-derived neurotrophic factor valine(66) methionine variant
Biol Psychiatry. 2009 Aug 1;66(3):293-7
Mirakhur A, Moorhead TWJ, Stanfield AC, McKirdy J, Sussmann JE, Hall J, Lawrie SM, Johnstone EC, McIntosh AM

This article was published on Oct 5, 2011


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