Dr Kathryn Evans
- Centre for Genomic and Experimental Medicine
- MRC Institute of Genetics and Molecular Medicine
Contact details
- Email: Kathy.Evans@ed.ac.uk
Address
- Street
-
Centre for Genomic & Experimental Medicine MRC Institute of Genetics & Molecular Medicine The University of Edinburgh Western General Hospital Crewe Road South
- City
- Edinburgh
- Post code
- EH4 2XU
Background
Following my PhD I moved to a postdoctoral post at the Wellcome Trust Sanger Institute, where I was involved in the Human Genome Project. I was recruited back to the MRC HGU to lead the genetic and physical mapping of a genomic region linked to bipolar disorder in a large family. Since moving to the University of Edinburgh, to what is now CGEM, my research has diversified, mainly to other areas of psychiatric and dementia research. Ongoing work in my group spans genetics, epigenetics, bioinformatics and functional (cell-based) analyses. In addition to research, I am CGEM Post-Graduate Convenor and teach students on MSc and PhD programmes.
Qualifications
Degree 1986 – 1990: The University of Edinburgh. 2i BSc (Hons) Biological Sciences (Genetics).
PhD 1990 – 1994: The University of Edinburgh /MRC Human Genetics Unit, Edinburgh. Mapping a balanced translocation t(1:11)(q42.2;q21) linked to schizophrenia.
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Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD
In:
EBioMedicine, vol. 43, pp. 576-586
DOI: https://doi.org/10.1016/j.ebiom.2019.03.072
Research output: Contribution to Journal › Article (Published) -
Epigenome-wide analyses identify DNA methylation signatures of dementia risk
In:
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, vol. 12
DOI: https://doi.org/10.1002/dad2.12078
Research output: Contribution to Journal › Article (Published) -
Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles
In:
Genome Medicine, vol. 13
DOI: https://doi.org/10.1186/s13073-020-00808-4
Research output: Contribution to Journal › Article (Published) -
Loss of SORCS2 is Associated with Neuronal DNA Double-Strand Breaks
In:
Cellular and molecular neurobiology
DOI: https://doi.org/10.1007/s10571-021-01163-7
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Epigenome-wide association study of alcohol consumption in N = 8161 individuals and relevance to alcohol use disorder pathophysiology: identification of the cystine/glutamate transporter SLC7A11 as a top target
In:
Molecular Psychiatry
DOI: https://doi.org/10.1038/s41380-021-01378-6
Research output: Contribution to Journal › Article (E-pub ahead of print)