Neil Henderson's lab is interested in the cellular and molecular mechanisms that drive organ fibrosis, and also the pathways which are responsible for efficient wound healing and healthy tissue regeneration following injury.
Organ fibrosis (scarring) is a major cause of morbidity and mortality worldwide, and as yet there are no effective anti-fibrotic treatments. My lab is interested in the cellular and molecular mechanisms that drive organ fibrogenesis, and also the molecular pathways which are responsible for efficient wound healing and healthy tissue regeneration following injury. By understanding more about how organs scar, heal and regenerate we hope to develop new treatments for patients with fibrotic diseases.
Neil Henderson undertook medical training in Edinburgh and London before completing a Wellcome Trust funded PhD at the MRC Centre for Inflammation Research, Edinburgh. He then trained in hepatology and was awarded a Wellcome Trust Clinician Scientist Fellowship, during which time he spent a 3 year post-doctoral period based in Dean Sheppard’s lab at the University of California, San Francisco, USA. Neil has since been awarded a Wellcome Trust Senior Research Fellowship in Clinical Science to investigate novel mechanisms of organ fibrosis and regeneration, using cutting edge techniques including intravital imaging approaches combined with the rapidly evolving field of transgenic mouse technology.