Dr Cornelia Roesl

To find new ways of detecting early signs of Motor-Neurone-Disease, monitoring its progression, and evaluating the efficiency of treatments.

Contact type
Person
First name
Cornelia
Surname
Roesl
Title
Dr
Organisation 1
Hugh Robson Building
Organisation 2
15 George Square
Organisation 3
Edinburgh EH8 9XD
Work phone
+44 (0) 131 651 1779
Email
Cornelia.roesl@ed.ac.uk

Personal profile

  • 2016 - present: Postdoctoral Research Fellow, Centre for Discovery Brain Sciences, University of Edinburgh, Scotland
  • 2013 - 2015: Postdoctoral Research Fellow, MRC Centre for Reproductive Health, University of Edinburgh, Scotland
  • 2013 PhD in Biochemistry, Massey University Palmerston North, New Zealand
  • 2009 Diagnostic Assistant, Institute of Human Genetics, Hannover Medical School, Germany
  • 2008 Research Associate, Department of Otolaryngology, Hannover Medical School, Germany
  • 2007 Research Associate, BioDoc laboratory Hannover, Germany
  • 2002- 2007 German Diplom (MSc) in Biochemistry, Leibniz University Hannover, Germany

Research

I play a crucial role in a team doing research to find new ways of detecting early signs of Motor-Neurone-Disease, monitoring its progression, and evaluating the efficiency of treatments. I am developing molecular probes for labelling neuromuscular junctions and that will give us direct optical visualisation of how the disease progresses.

Selected publications

J. Stephens, A.H. Schiemann, C. Roesl, D. Miller, S. Massey, N. Pollock, T. Bulger, K. Stowell, Functional Analysis of RYR1 variants linked to Malignant Hyperthermia, Temperature, 2016; 3(2): 328-339

A. Willems, C. Roesl, RT Mitchell, L. Milne, N. Jefferey, S. Smith, G. Verhoeven, LB Smith, Sertoli cell Androgen Receptor signalling in adulthood is essential for post-meiotic germ cell development, Mol Reprod. Dev., 2015 Sep;82(9):626-7

C. Roesl, K. Sato, A. Schiemann, N. Pollock, K.M. Stowell, Functional characterisation of the R2452W ryanodine receptor variant associated with malignant hyperthermia susceptibility, Cell Calcium, 2014 Sep;56(3):195-201

K. Sato, C. Roesl, N. Pollock, K.M. Stowell, Skeletal Muscle Ryanodine Receptor Mutations Associated with Malignant Hyperthermia Showed Enhanced Intensity and Sensitivity to Triggering Drugs When Expressed in Human Embryonic Kidney Cells, Anaesthesiology, 2013 Jul; 119:111-118

G. Paasche, P. Ceschi, M. Loebler, C. Roesl, P. Gomes, A. Hahn, H.W. Rohm, K. Sternberg, T. Lenarz, K.P. Schmitz, S. Barchikowski, T. Stoever, Effects of metal ions on fibroblasts and spiral ganglion cells, Journal of Neuroscience Research, 2011 Apr; 89(4):611–617 

E.A. El-Harith*, C. Roesl*, M. Ballmaier, M. Germeshausen, H. Frye-Boukhriss, N. von Neuhoff, C. Becker, G. Nürnberg, P. Nürnberg, M.A.M. Ahmed,J. Hübener, J. Schmidtke, K. Welte, M. Stuhrmann, Familial thrombocytosis caused by the novel germ-line mutation p.Pro106Leu in the MPL gene, British Journal of haematology, 2009 Jan;144(2):185-94 (*authors contributed equally)

 

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