Aims to build on findings from SFXN3 and other potential candidates from the proteomic screen to develop potential therapies for patients suffering with Parkinson's Disease. Contact type Person First name Leire Surname Ledahawsky Role PhD Student - Gillingwater Lab Organisation 1 Hugh Robson Building Organisation 2 15 George Square Organisation 3 Edinburgh EH8 9XD Work phone +44 (0) 131 651 1512 Email Leire.Ledahawsky@ed.ac.uk Personal Profile 2017-Present, PhD in Precision Medicine, University of Edinburgh 2016-2017, MRes in Health Sciences, University of Bristol 2012-2016, Biomedical Sciences (Neuroscience) BSc (Hons), University of Edinburgh Research Synapses are a primary pathological target across several neurodegenerative diseases, including Parkinson’s Disease, Alzheimer’s disease and motor neuron disease. The mitochondrial protein Sideroflexin 3 (SFXN3) was recently identified as a potential modulator of synaptic stability. My project aims to identify molecular interactors of SFXN3 and better understand its role in neurodegeneration in the hopes of developing SFXN3 as a therapeutic target against neurodegenerative diseases. Relevant Publications Huang, Y.T., van der Hoorn, D., Ledahawsky, L.M., Motyl, A.A., Jordan, C.Y., Gillingwater, T.H. and Groen, E.J., 2019. Robust comparison of protein levels across tissues and throughout development using standardized quantitative western blotting. JoVE (Journal of Visualized Experiments), (146), p.e59438. This article was published on 2022-10-17
Contact type Person First name Leire Surname Ledahawsky Role PhD Student - Gillingwater Lab Organisation 1 Hugh Robson Building Organisation 2 15 George Square Organisation 3 Edinburgh EH8 9XD Work phone +44 (0) 131 651 1512 Email Leire.Ledahawsky@ed.ac.uk
