The early impact of macrophages on tumour development. Contact type Person First name Kelda Surname Chia Role PhD Student - Sieger Group Organisation 1 The Chancellor's Building Organisation 2 49 Little France Crescent Organisation 3 EH16 4SB Work phone +44 (0) 131 242 9411 Email kelda.chia@ed.ac.uk Personal Profile 2014 – present: PhD in Neuroscience, University of Edinburgh 2013 – 2014: MSc (by Research) in Integrative Neuroscience, University of Edinburgh 2009 – 2013: BSc in Neuroscience, University of St Andrews Research Within the tumour microenvironment, macrophages contribute to a significant proportion of the tumour mass and have been demonstrated to promote tumour growth and expansion. However, their role in the earliest stages of tumour initiation and development remains unknown. Therefore, the focus of my PhD has been to investigate the early impact of macrophages on tumour development, in particular the role of microglia and its impact within the brain tumour microenvironment. Recent publications Chia K., Mazzolini J., Mione M. & Sieger D. (2018) Tumor initiating cells induce Cxcr4-mediated infiltration of pro-tumoral macrophages into the brain. eLIFE, 7:e31918. DOI: https://doi.org/10.7554/eLife.31918 Mazzolini J., Chia K. & Sieger D. (2018) Isolation and RNA extraction of neurons, macrophages and microglia from larval zebrafish brains. J. Vis. Exp. (134), e57431, doi:10.3791/57431. This article was published on 2022-10-17
Contact type Person First name Kelda Surname Chia Role PhD Student - Sieger Group Organisation 1 The Chancellor's Building Organisation 2 49 Little France Crescent Organisation 3 EH16 4SB Work phone +44 (0) 131 242 9411 Email kelda.chia@ed.ac.uk
