Mandy Johnstone is a Wellcome Trust Clinical Research Fellow & Honorary Consultant Psychiatrist.
Dr Johnstone completed her PhD in Developmental Neurobiology at King’s College London.
She qualified in Medicine at the University of Glasgow and then went on to train as a psychiatrist at The Institute of Psychiatry and then in Edinburgh where she is now a Wellcome Trust Clinical Fellow and Honorary Consultant Psychiatrist.
Dr Johnstone’s research interests are in the clinical and molecular mechanisms underlying schizophrenia and affective disorders. Over the past several years she has been investigating whether copy number variants (CNVs) contribute to susceptibility in families multiply affected with schizophrenia and bipolar affective disorder.
Dr Johnstone's research is now focused on how schizophrenia risk is conferred at a cellular level through comparative studies of neural tissue derived from individuals with and without disease-associated mutations. Her goal is to better understand the molecular pathophysiology of schizophrenia, and other neurodevelopmental disorders, using human induced pluripotent stem cells (hiPSCs) as in vitro models.
Her research is funded by a fellowship from The Wellcome Trust.