Biomedical Sciences

New Frontiers and Old Tricks - Edinburgh Pharmacology Symposium

The Edinburgh Pharmacology Symposium 2016 will take place on Thursday 5th May.

REGISTRATION NOW OPEN AT: http://edin.ac/1Ue1umF

PROGRAMME

Opening Address: Professor JS Kelly

9.00-10.45am Session 1 - Small molecule modulation of gene expression

Chair: Professor Mark Evans

 

Plenary Lecture - Selective modulation of gene expression using bromodomain inhibitors

Dr Rab Prinjha, VP Head of Epigenetics DPU,

Immunoinflammation TA Unit, GSK Medicines Research Centre, Stevenage, UK.

 

Therapeutic potential of micro-RNA

Professor Andy Baker, BHF Professor of Translational, Cardiovascular Sciences,

Gustav Born Chair of Vascular Biology, Centre for Cardiovascular Science, University of Edinburgh.

 

Why target DNA modification reprogramming in cancer?

Professor Richard Meehan, Chromosomes and Gene Expression Programme Leader,

Institute of Genetics and Molecular Medicine, University of Edinburgh.

 

COFFEE

 

11.15-12.45pm Session 2 - Subunit- and subtype-selective modulation of enzymes and receptors: delivering cell and system specificity

Chair: Dr Christos Gkogas

 

Subunit-selective modulation of AMPK: from cell to system

Professor Mark Evans, Chair of Cellular Pharmacology,

Centre for Integrative Physiology, University of Edinburgh

 

Pharmacological modulation of 5alpha-reductase

Dr Dawn Livingstone, Lecturer,

Centre for Integrative Physiology, University of Edinburgh.

 

Enhanced analgesia from combined targeting of a receptor:channel signalling complex

Professor Sue Fleetwood-Walker, Chair of Sensory Neuroscience,

Centre for integrative Physiology, University of Edinburgh.

 

LUNCH

 

2.00-3.30pm Session 3 Overcoming barriers to innovation in academic drug discovery

Chair: Professor Michael Eddleston

 

Discovery of KMO inhibitors for potential treatment of organ failure

Dr Scott Webster, Senior Lecturer and Director of Drug Discovery Core,

Centre for Cardiovascular Science, University of Edinburgh

 

Targeting the Glycolytic Pathway for Trypanocidal Drugs

Prof Malcolm Walkinshaw, Chair of Structural Biochemistry and Director, 

Centre for Translational and Chemical Biology, University of Edinburgh.

 

Scaffold hopping approaches to novel Autotaxin inhibitors

Dr Craig Jamieson, Senior Lecturer, Pure and Applied Chemistry,

University of Strathclyde, Glasgow, UK.

 

COFFEE

 

4.00-5.30pm Session 4 Pro-drugs and combinatorial therapies: tipping the balance towards a cancer cure

Chair: Dawn Livingstone

 

Novel Inhibitors of Tryptophan Metabolism as Cancer Immunotherapies

Dr Philip Cowley, Head of Chemistry, IOMET Pharma, Edinburgh, UK

 

Understanding resistance to cancer therapies

Professor Val Brunton, Chair of Cancer Therapeutics,

Centre for Cancer Therapeutics, University of Edinburgh

 

The role of tumour microenvironment in prostate cancer resistance to androgen deprivation therapy

Dr Binzhi Qian, Chancellor’s Fellow & CRUK Career Development Fellow

Edinburgh Cancer Research UK Centre & MRC University of Edinburgh Centre for Reproductive Health.

 

5.30-7pm Wine Reception

 

Registration and further information This event aims to provide a networking forum for research workers and clinicians with an interest in therapeutic developments and applications, by describing current projects and activities in the Edinburgh area.

It is supported by the University of Edinburgh and the British Pharmacological society ambassador scheme. Registration for this event is essential, the event is free of charge for undergraduates and PhD students and a nominal fee of £10 (Edinburgh staff) and £20 (External registrants) will be charged for participants.

Registration and payment is via University of Edinburgh ePay system: http://edin.ac/1Ue1umF

 

Further information

Please contact:

Prof A. Mark Evans

Prof Michael Eddleston

Dr Anne Leaver (BPS Ambassador)